Aromatic hydrocarbon receptor (AHR)
Aromatic hydrocarbon receptor (AHR) is a ligand activated transcription factor, which can mediate the toxic (including carcinogenic) reactions of polycyclic aromatic hydrocarbon compounds and also participate in some important biological processes, such as signal transduction, cell differentiation, and cell apoptosis.
AHR is found in human lung, liver, kidney, placenta, palatine tonsil, b-lymphocyte and other tissues and cells. AHR regulates growth, development and physiological functions, and promotes the occurrence and development of some cancers (breast cancer and ovarian cancer, etc.). Aromatic hydrocarbon receptors as important environmental receptors, AHR is the bridge of environmental factors and the human body, to participate in a variety of important biological functions such as regulating cell proliferation, differentiation and mediated inflammatory process. AHR is closely related to the occurrence of a variety of tumors, not only to participate in environmental pollution induced skin tumor, recently found that may also participated in the uv induced skin cancer. AHR may be an effective prevention and treatment of skin tumor targets. Aromatic hydrocarbon receptor is a kind of cytoplasmic transcription factor, participate in the immune response, small molecule substance metabolic, hormonal, steady state and melanin synthesis, such as a variety of biological processes.
In recent years, the study found that aromatic hydrocarbon receptors mediated exogenous small molecule chemicals that interfere with the immune system, allergy and autoimmune reaction that generates the body, its developing in autoimmune skin disease also play a role. An overview of the aromatic hydrocarbon receptors signaling pathways, immune function and its correlation with autoimmune skin disease research progress, further understand the pathogenesis of autoimmune skin disease, provide new way for the treatment of immune diseases.
At present, DLDEVELOP co. LTD has developed corresponding AHR Elisa products. To get more information, you could contact our professional staff directly or directly to our website:
https://dldevelop.com/Research-reagent/dl-ahr-hu.html https://dldevelop.com/Research-reagent/dl-ahr-mu.html https://dldevelop.com/Research-reagent/dl-ahr-ra.html
AHR is found in human lung, liver, kidney, placenta, palatine tonsil, b-lymphocyte and other tissues and cells. AHR regulates growth, development and physiological functions, and promotes the occurrence and development of some cancers (breast cancer and ovarian cancer, etc.). Aromatic hydrocarbon receptors as important environmental receptors, AHR is the bridge of environmental factors and the human body, to participate in a variety of important biological functions such as regulating cell proliferation, differentiation and mediated inflammatory process. AHR is closely related to the occurrence of a variety of tumors, not only to participate in environmental pollution induced skin tumor, recently found that may also participated in the uv induced skin cancer. AHR may be an effective prevention and treatment of skin tumor targets. Aromatic hydrocarbon receptor is a kind of cytoplasmic transcription factor, participate in the immune response, small molecule substance metabolic, hormonal, steady state and melanin synthesis, such as a variety of biological processes.
In recent years, the study found that aromatic hydrocarbon receptors mediated exogenous small molecule chemicals that interfere with the immune system, allergy and autoimmune reaction that generates the body, its developing in autoimmune skin disease also play a role. An overview of the aromatic hydrocarbon receptors signaling pathways, immune function and its correlation with autoimmune skin disease research progress, further understand the pathogenesis of autoimmune skin disease, provide new way for the treatment of immune diseases.
At present, DLDEVELOP co. LTD has developed corresponding AHR Elisa products. To get more information, you could contact our professional staff directly or directly to our website:
https://dldevelop.com/Research-reagent/dl-ahr-hu.html https://dldevelop.com/Research-reagent/dl-ahr-mu.html https://dldevelop.com/Research-reagent/dl-ahr-ra.html
